Perioperative medicine & outcomes
Amino Acid Infusion for Perioperative Functional Renal Protection: A Meta-analysis
Pooled resultResult — go to the resultRelative risk 0.66 95% CI 0.47–0.94Authors' conclusion
This meta-analysis suggests that AA administration likely decreased the perioperative incidence of AKI.
Study context
- Population
- Perioperative patients
- Participants
- 4,544 patients · 15 studies
- Comparison
- Intravenous amino acid infusion vs any comparator
- Outcome
- AKI
- Follow-up
- Longest
Methodological detailsrandom effects, Bayesian analysis
- Random effects
- Bayesian analysis
Pooled result
As reported in the abstract
Relative risk
0.66
95% CI 0.47–0.94
P = 0.02
Events by group
AA vs Controls
RR 0.66 (95% CI 0.47–0.94); P = 0.02
- Probability of acute kidney injury (AKI) reduction with amino acids (AA) (Bayesian)
- 99.1%
Further pooled results
- AA decreased serum creatinine and hospital LOS and increased eGFR
Original publication
Amino Acid Infusion for Perioperative Functional Renal Protection: A Meta-analysis. J Cardiothorac Vasc Anesth. Published 22 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →