ICU sedation, delirium & recovery
Anabolic androgen therapy in critically ill adults: A systematic review and meta-analysis
Authors' conclusion
Together, we judged risk of bias as 'some concerns' in 3 trials and 'high' in the final trial, and ultimately found that the effects of anabolic-androgen therapy on patient-important outcomes uncertain.
Study context
- Population
- Adults (≥18 years) admitted to ICU4 randomized control trials (RCTs)
- Comparison
- Anabolic androgen therapy vs placebo or standard of care
- Outcome
- Patient-important outcomes: mortality, ICU and hospital LOS, duration of mechanical ventilation
Methodological detailsrandom-effects model, GRADE
- Random-effects model
- GRADE
Pooled result
As reported in the abstract
Patient-important outcomes
- Effects of anabolic androgen therapies (AAT) on patient-important outcomes uncertain
Further pooled results
Risk of bias
- 'Some concerns' in 3 trials
- 'High' in 1 trial
Original publication
Anabolic androgen therapy in critically ill adults: A systematic review and meta-analysis. J Crit Care. Published 29 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →