Anaesthesia for caesarean delivery in patients with placenta accreta spectrum: a retrospective cohort study in two referral centres in Ireland (2017–2024)
Authors' conclusion
General anaesthesia was performed in the majority of placenta accreta spectrum cases although in many patients this was combined with neuraxial anaesthesia. General anaesthesia was associated with greater maternal blood loss and poorer neonatal outcomes, although these findings should be interpreted with caution given the performance of general anaesthesia in all non-elective cases.
Study context
- Population
- Women with placenta accreta spectrum undergoing caesarean delivery in two tertiary referral maternity hospitals in Ireland, 2017–2024
- Participants
- 75 women
- Exposure
- GA only vs combined neuraxial and GA vs neuraxial anaesthesia only
- Outcome
- Anaesthetic approach
Methodological detailstwo tertiary referral centres
- Two tertiary referral centres
Main finding
As reported in the abstract
Combined neuraxial and GA
50.7%
- Patients receiving GA at some point during surgery
- 63 (84%)
Observational data: associations, not effects.
Further findings
Hysterectomy (association with GA)
| OR (95% CI) | P value | ||
|---|---|---|---|
| GA | 6.6 (1.34–32.9) | P = 0.02 | |
| 0.050.21520Odds ratio (log scale) |
| Outcome | OR (95% CI) | P value |
|---|---|---|
| Blood loss (association with GA)Increased blood loss | 1.001 (1.00–1.00) | P = 0.043 |
Neonatal outcomes (association with GA)
- Reduced Apgar scores at 5 and 10 min
- P < 0.011
- Greater need for neonatal intubation
- P = 0.002
Original publication
Anaesthesia for caesarean delivery in patients with placenta accreta spectrum: a retrospective cohort study in two referral centres in Ireland (2017–2024). Int J Obstet Anesth. Published 6 December 2025. doi:10.
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