Analgesic benefits of regional anesthesia in the perioperative management of transition-related surgery: a systematic review
Authors' conclusion
Despite the ever-growing demand for transition-related surgery, the relative analgesic effectiveness of regional anesthesia for transgender patients undergoing transition-related surgery is very understudied and insufficient to guide clinical practice.
Study context
- Population
- Patients undergoing chest and/or genital transition-related surgery10 reports
- Participants
- 293 patients
- Comparison
- Regional anaesthetic techniques vs parenteral analgesia alone
- Outcome
- Pain severity and opioid requirements
- Follow-up
- First postoperative day
Methodological detailsnarrative synthesis, 1863 records identified; 2 RCTs, 3 cohort studies, 5 case reports/series included
- Narrative synthesis
- 1863 records identified; 2 RCTs, 3 cohort studies, 5 case reports/series included
Pooled result
As reported in the abstract
Pain severity and opioid requirements on the first postoperative day
Three studies directly compared regional techniques with parenteral analgesia alone
3
Two studies: lower pain scores and opioid requirements with nerve blocks vs none
2
Further pooled results
Chest surgery reports
- 4 reports, 243 patients; transgender men undergoing mastectomy with pectoralis nerve blocks or local anesthetic instillation devices
- 86%
Genital surgery reports
- 6 reports, 50 patients; transgender women undergoing vaginoplasty with ESP blocks or epidural anesthesia
- 56%
Safety
Complications related to regional anesthetic techniques
- Rare
Original publication
Analgesic benefits of regional anesthesia in the perioperative management of transition-related surgery: a systematic review. Reg Anesth Pain Med. Published 6 May 2024. doi:10.
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