Cardiothoracic & vascular anesthesia

Pecto-intercostal fascial plane block with or without rectus sheath block in cardiac surgery: a prospective, randomized, double-blind placebo-controlled study

Reg Anesth Pain MedPublished Randomised controlled trial

Authors' conclusion

Adding bilateral RSB to bilateral PIFB did not improve pain control or other outcomes for patients undergoing cardiac surgery.

Study context

Population
Patients undergoing cardiac surgery with median sternotomy and subxiphoid chest tubes
Participants
62 patients
Comparison
Bupivacaine vs Placebo
Primary endpoint
Pain at rest and with deep breathing
Follow-up
First 24 hours after surgery
Methodological detailssingle-centre, double-blind, placebo-controlled
  • Single-centre
  • Double-blind
  • Placebo-controlled

Primary result

As reported in the abstract

first 24 hours

Placebo

93.37

mean · SD 41.38

Bupivacaine

86.11

mean · SD 42.78

Bupivacaine vs Placebo: P = 0.51 · Bupivacaine vs Placebo: P = 0.57

Secondary outcomes

Mean

OutcomeBupivacainePlaceboP value
Pain with deep breathing (AUC) · first 24 hoursPart of primary outcome128.78 (SD 47.08)135.55 (SD 43.74)P = 0.57

Opioid consumption at 24 and 48 h, incentive spirometry, time to extubation, hospital and ICU LOS, QoR-15

No differences between groups

Original publication

Pecto-intercostal fascial plane block with or without rectus sheath block in cardiac surgery: a prospective, randomized, double-blind placebo-controlled study. Reg Anesth Pain Med. Published 21 September 2025. doi:10.1136/rapm-2025-106954

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