Pediatric anesthesia & critical care
Analgesic Effects of Regional Analgesic Techniques in Pediatric Inguinal Surgeries: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Authors' conclusion
The quadratus lumborum and transversus abdominis plane blocks had the longest time to the first rescue analgesic and the least rescue analgesic requirement for pediatric inguinal surgeries.
Study context
- Population
- Children undergoing inguinal surgery
- Participants
- 4,636 children · 69 RCTs
- Comparison
- 10 regional analgesic techniques vs control
- Outcome
- Time to first rescue analgesic after surgery
Methodological detailsrandom-effects
- Random-effects
Pooled result
As reported in the abstract
Each group vs controlDifference, hours (95% CI)
QL block
7.7(5.0–10.3)
TAP block
6.0(3.9–8.2)
Further pooled results
| Outcome | Difference (hours) (95% CI) | |
|---|---|---|
| Time to first rescue analgesic, orchidopexy (subgroup)Caudal block vs Control · only technique significantly prolonging time vs control | 4.1 (0.7–7.5) | |
| −50510Difference, hours (linear scale) |
Time to first rescue analgesic, inguinal hernia repair (subgroup)
- QL block significantly prolonged time vs all other regional analgesics
Analgesic effect of wound infiltration and landmark-based ilioinguinal-iliohypogastric block
- Relatively poor analgesic effects vs other regional analgesics
Safety
Serious adverse effects related to the regional analgesic techniques
- No serious adverse effects reported in any included study
Original publication
Analgesic Effects of Regional Analgesic Techniques in Pediatric Inguinal Surgeries: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Anesth Analg. Published 15 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →