Pediatric anesthesia & critical care
Analgesic Efficacy of Bilateral Ultrasound-Guided Transversus Thoracic Muscle Plane Block Versus Erector Spinae Plane Block in Pediatric Patients Undergoing Corrective Cardiac Surgeries: A Randomized Controlled Study
Authors' conclusion
Both TTPB and ESPB reduced nociception and appeared comparable in providing perioperative analgesia as they reduced pain scores and intraoperative and postoperative narcotic dosage, which facilitated early extubation.
Study context
- Population
- Pediatric patients undergoing corrective cardiac surgeries, tertiary pediatric university hospital, November 2022 to August 2023
- Participants
- 60 patients
- Comparison
- Bilateral US-guided transversus thoracic plane block (TTPB) vs erector spinae plane block (ESPB) vs control
- Controln = 20reference
- ESPBn = 20
- Primary endpoint
- Total intraoperative fentanyl consumption
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
Intraoperative fentanyl consumption
TTPB
3.4
± 2.9
Control
6.7
± 4.2
Mean difference (95% CI)P value
TTPB vs Control
3.35(0.84–5.86)
P = 0.006TTPB vs ESPBcomparable
1.2(−1.31 to 3.71)
P = 0.486Secondary outcomes
| Outcome | Control | ESPB | TTPB | Mean difference (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Total fentanyl consumption in the ICUTTPB vs Control | 4.6 ± 4.25 | — not stated in the abstract | 1.1 ± 1.54 | 3.55 (1.5–5.6) | P = 0.001 | |
| Time to first rescue analgesiaTTPB vs Control | 1.95 ± 3.5 | 4.9 ± 4.4 | 5.15 ± 4.21 | −3.2 (−5.68 to −0.72) | P = 0.04 | |
| Time to first rescue analgesiaESPB vs TTPB | −0.25 (−3.01 to 2.51) | P = 0.979 | ||||
| Time to first rescue analgesiaESPB vs Control · non-significantly longer | −2.95 (−5.5 to −0.4) | P = 0.064 | ||||
| −10−50510Difference (linear scale) |
— not stated in the abstract
| Outcome | Control | ESPB | TTPB | Relative risk (95% CI) | P value | |
|---|---|---|---|---|---|---|
| Fast-track extubationTTPB vs ESPB | 30% | 50% | 85% | 0.58 (0.36–0.94) | P = 0.018 | |
| Fast-track extubationTTPB vs Control | 0.35 (0.17–0.706) | P < 0.001 | ||||
| Ultrafast-track extubationTTPB vs Control | 15% | — not stated in the abstract | 60% | 0.25 (0.08–0.75) | P = 0.007 | |
| 0.050.21520Relative risk (log scale) |
— not stated in the abstract
Total fentanyl consumption in the ICU
- Other pairwise comparisons comparable between the groups
Original publication
Analgesic Efficacy of Bilateral Ultrasound-Guided Transversus Thoracic Muscle Plane Block Versus Erector Spinae Plane Block in Pediatric Patients Undergoing Corrective Cardiac Surgeries: A Randomized Controlled Study. J Cardiothorac Vasc Anesth. Published 3 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →