Pediatric anesthesia & critical care

Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery: A systematic review and Meta-analysis of randomized controlled trials

J Clin AnesthPublished Systematic review and meta-analysis of randomised trials

Pooled resultResult — go to the resultSMD −1.51 95% CI −2.39 to −0.64

Authors' conclusion

ESPB provides effective and safe perioperative analgesia in pediatric patients undergoing elective surgery under general anesthesia.

Study context

Population
Pediatric patients undergoing elective surgery under GA
Participants
919 patients · 17 randomized controlled studies (RCTs)
Comparison
Ultrasound-guided erector spinae plane block (ESPB) vs controls
  • ESPBn = 461
  • No blockn = 269reference
  • Other blockn = 189reference
Outcome
Cumulative opioid consumption after surgery (IV morphine milligram equivalents)

Pooled result

As reported in the abstract

SMD

−1.51

95% CI −2.39 to −0.64

P = 0.0002

ESPB vs No block and other blocks
SMD −1.51 (95% CI −2.39 to −0.64); P = 0.0002

Further pooled results

Intraoperative opioid consumption

Significantly reduced with ESPB vs control

Average pain scores · up to 24 h after surgery

Lowered with ESPB; lower at most time points for 24 h

Time to first request for rescue analgesia

Extended with ESPB

Patients requiring rescue analgesics

Decreased with ESPB

Parental satisfaction

Improved with ESPB

Safety

Postoperative vomiting

Reduced incidence with ESPB vs no block/sham block

Original publication

Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery: A systematic review and Meta-analysis of randomized controlled trials. J Clin Anesth. Published 10 August 2024. doi:10.1016/j.jclinane.2024.111575

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