Pediatric anesthesia & critical care
Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery: A systematic review and Meta-analysis of randomized controlled trials
Pooled resultResult — go to the resultSMD −1.51 95% CI −2.39 to −0.64Authors' conclusion
ESPB provides effective and safe perioperative analgesia in pediatric patients undergoing elective surgery under general anesthesia.
Study context
- Population
- Pediatric patients undergoing elective surgery under GA
- Participants
- 919 patients · 17 randomized controlled studies (RCTs)
- Comparison
- Ultrasound-guided erector spinae plane block (ESPB) vs controls
- ESPBn = 461
- No blockn = 269reference
- Other blockn = 189reference
- Outcome
- Cumulative opioid consumption after surgery (IV morphine milligram equivalents)
Pooled result
As reported in the abstract
SMD
−1.51
95% CI −2.39 to −0.64
P = 0.0002
ESPB vs No block and other blocks
SMD −1.51 (95% CI −2.39 to −0.64); P = 0.0002
Further pooled results
Intraoperative opioid consumption
- Significantly reduced with ESPB vs control
Average pain scores · up to 24 h after surgery
- Lowered with ESPB; lower at most time points for 24 h
Time to first request for rescue analgesia
- Extended with ESPB
Patients requiring rescue analgesics
- Decreased with ESPB
Parental satisfaction
- Improved with ESPB
Safety
Postoperative vomiting
- Reduced incidence with ESPB vs no block/sham block
Original publication
Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery: A systematic review and Meta-analysis of randomized controlled trials. J Clin Anesth. Published 10 August 2024. doi:10. 1016/ j. jclinane. 2024. 111575
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