Analgesic efficacy of inter-semispinal fascial plane block in Patients undergoing Cervical Spine Surgery through Posterior Approach: a randomized controlled trial
Authors' conclusion
Inter-semispinal plane block (ISPB) represents an effective analgesic technique and reduces opioid consumption in both intra- and postoperative settings. Moreover, the ISPB could significantly decrease opioid-associated side effects.
Study context
- Population
- Patients planned for cervical spine surgery via the posterior approach
- Participants
- 52 patients
- Comparison
- Bilateral inter-semispinal plane block (ISPB) plus GA vs GA only
- ISPBn = 26
- Controln = 26reference
- Primary endpoint
- Total perioperative opioid consumption: co-primary intraoperative fentanyl and morphine consumption in first 24 h postoperatively
Methodological detailsprospective, 1:1 allocation
- Prospective
- 1:1 allocation
Primary result
As reported in the abstract
Intraoperative fentanyl and 24-h postoperative morphine
ISPB
175
median · range 110–220 · μg
Control
290
median · range 110–350 · μg
ISPB
7
median · range 5–12 · mg
Control
12
median · range 8–21 · mg
Secondary outcomes
Numerical rating scores (NRS) pain scores · first 12 h postoperatively
- NRS significantly lower in ISPB vs control
Intraoperative mean arterial pressure (MAP) and HR
- Significant MAP increase during surgery in control
- P < 0.001
- No significant MAP or HR differences between intraoperative time points in ISPB
Safety
Opioid side effects (nausea, vomiting, sedation)
- Incidence significantly greater in control vs ISPB
Original publication
Analgesic efficacy of inter-semispinal fascial plane block in Patients undergoing Cervical Spine Surgery through Posterior Approach: a randomized controlled trial. Anaesth Crit Care Pain Med. Published 7 March 2023. doi:10.
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