Cardiothoracic & vascular anesthesia
Effect of Bilateral Pectointercostal Fascial Plane Block on Chronic Postsurgical Pain After Coronary Artery Bypass Grafting: A Randomized Clinical Trial
Primary resultResult — go to the resultOdds ratio 0.42 95% CI 0.13–1.36Authors' conclusion
Bilateral PIF block did not demonstrate a statistically significant decrease in clinically relevant CPSP at 3 months after CABG.
Study context
- Population
- Adults undergoing elective coronary artery bypass grafting (CABG) via median sternotomy, tertiary referral hospital
- Participants
- 50 adults
- Comparison
- PIF vs Standard care
- PIFn = 25
- Standard caren = 25reference
- Primary endpoint
- Clinically relevant chronic postsurgical pain (CPSP; ICD-11 criteria plus functional interference on the Brief Pain Inventory)
- Follow-up
- 3 months
Methodological detailssingle-centre, prospective, blinded postoperative outcome assessment
- Single-centre
- Prospective
- Blinded postoperative outcome assessment
Primary result
As reported in the abstract
Odds ratio
0.42
95% CI 0.13–1.36
P = 0.145
Events by treatment group
PIF vs Standard care
OR 0.42 (95% CI 0.13–1.36); P = 0.145
Secondary outcomes
Cumulative 72-hour morphine consumption · exploratory secondary analyses
nominal p < 0.001
Acute pain scores at rest and with movement · first 72 postoperative hours
- Lower in the PIF group (all p < 0.001)
- Exploratory secondary analyses
Safety
- No block-related complications occurred
Original publication
Effect of Bilateral Pectointercostal Fascial Plane Block on Chronic Postsurgical Pain After Coronary Artery Bypass Grafting: A Randomized Clinical Trial. J Cardiothorac Vasc Anesth. Published 19 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →