Cardiothoracic & vascular anaesthesia
A Single-blind, Randomized Controlled Trial Comparing Postoperative Analgesic Effects of Superficial and Deep Parasternal Intercostals Blocks in Patients Undergoing Coronary Artery Bypass Grafting Surgery
Authors' conclusion
Both parasternal intercostal blocks improved postoperative analgesia compared with standard care.
Study context
- Population
- Adults aged 45–80 years, ASA III–IV, scheduled for elective isolated coronary artery bypass grafting (CABG) via median sternotomy
- Participants
- 75 adults
- Comparison
- Deep parasternal intercostal plane block (DPIPB) vs superficial parasternal intercostal plane block (SPIPB)
- Primary endpoint
- Cumulative tramadol administration
- Follow-up
- 24 hours
Methodological detailsprospective, single-blind, single-centre
- Prospective
- Single-blind
- Single-centre
Primary result
As reported in the abstract
Cumulative 24-hour tramadol administration
P < 0.001
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Requiring high-dose tramadolDPIPB vs Control | 0.18 (0.06–0.56) | P = 0.003 | |
| Requiring high-dose tramadolSPIPB vs Control | 0.52 (0.23–1.18) | P = 0.095 | |
| Requiring high-dose tramadolDPIPB vs SPIPB · lower tramadol use | 0.34 (0.16–0.72) | P < 0.001 | |
| 0.050.21520Odds ratio (log scale) |
| Outcome | P value |
|---|---|
| Pain scores · all time pointsSPIPB, DPIPB vs Control | P < 0.05 |
- Pain scores: significantly lower in both block groups; DPIPB most pronounced
Safety
- No block-related complications observed
Original publication
A Single-blind, Randomized Controlled Trial Comparing Postoperative Analgesic Effects of Superficial and Deep Parasternal Intercostals Blocks in Patients Undergoing Coronary Artery Bypass Grafting Surgery. J Cardiothorac Vasc Anesth. Published 23 July 2025. doi:10.
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