Paediatric anaesthesia & critical care
Anesthesia for Endoscopic Strip Craniectomy Repair: A Single‐Center Retrospective Cohort Study
Authors' conclusion
We report a > 20% transfusion rate in our infant cohort mostly with metopic repairs.
Study context
- Population
- Infants undergoing endoscopic strip craniectomy for craniosynostosis, Great Ormond Street Hospital, UK, 2019–2024
- Participants
- 111 infants
- Exposure
- Single suture repair vs Bilateral or multisuture repair
- Outcome
- Red cell transfusion
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Overall red cell transfusion rate
1 in 5 children
Transfusion in metopic suture repair
18/67, 26%
Observational data: associations, not effects.
Further findings
| Outcome | Single suture repair | Bilateral or multisuture repair |
|---|---|---|
| Hb reduction, preop to postopMean, g/L | 26 (SD ±15 g/L) | 35 (SD ±15 g/L) |
| Preoperative Hb | 114 g/L (±11 g/L SD) | 118 g/L (±7.17 g/L SD) |
| Postoperative Hb | 87 g/L (±13 g/L SD) | 85.5 g/L (±14.29 g/L SD) |
- Surgical procedure time: All sutures 73 (SD ±23) min
- Surgical procedure time: Multisuture 96 (SD ±15) min
Hospital discharge and HDU care
- Discharged on Day 1 postoperatively
- 106 (95%)
- No children required high dependency care
Safety
Complications
- Inadvertent extubation on positioning
- 2
- Laryngospasm
- 1
- Minor transfusion reaction
- 1
Original publication
Anesthesia for Endoscopic Strip Craniectomy Repair: A Single‐Center Retrospective Cohort Study. Paediatr Anaesth. Published 7 July 2025. doi:10.
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