Cardiac arrest & resuscitation
Annual improvement trends in resuscitation outcome of patients defibrillated by laypersons after out-of-hospital cardiac arrests and compression-only resuscitation of laypersons
Main finding · Favorable outcomesResult — go to the resultAdjusted odds ratio 1.23 95% CI 1.13–1.34Authors' conclusion
In Japan, the outcomes of out-of-hospital cardiac arrest patients who were defibrillated by laypersons were considerably better in compression-only resuscitation of laypersons every year.
Study context
- Population
- Adults and children with witnessed OHCA defibrillated by laypersons, Japan national database, 2005–2019
- Participants
- 11,402 adults
- Exposure
- Compression-only cardiopulmonary resuscitation (CPR) vs conventional CPR by laypersons
- Outcome
- One-month survival and survival with good neurological outcome
- Follow-up
- One month
Methodological detailsinverse probability weighting using propensity score, multivariate logistic regression, trend analyses
- Inverse probability weighting using propensity score
- Multivariate logistic regression
- Trend analyses
Main finding
Favorable outcomes
Adjusted odds ratio
1.23
95% CI 1.13–1.34
Compression-only CPR vs Conventional CPR
adjusted OR 1.23 (95% CI 1.13–1.34)
As reported in the abstract
- Relative risk reduction, compression-only vs conventional
- 7.6%
- NNT, compression-only vs conventional
- 22.1
Observational data: associations, not effects.
Further findings
Proportion of compression-only resuscitation over time
- Increased dramatically, more than 50% from 2012
- P < 0.001
Favorable resuscitation outcomes over time
- Increased annually
- P < 0.001
- Favorable outcomes associated with recent years, male sex, younger age and shorter resuscitation start time
- Adjusted outcomes better with compression-only resuscitation in most years
Original publication
Annual improvement trends in resuscitation outcome of patients defibrillated by laypersons after out-of-hospital cardiac arrests and compression-only resuscitation of laypersons. Resuscitation. Published 19 December 2022. doi:10. 1016/ j. resuscitation. 2022. 12. 010
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