Anterior quadratus lumborum block in total hip arthroplasty: a two-center, randomized, placebo-controlled trial showing no additional benefit over multimodal analgesia
Authors' conclusion
Adding anterior QLB to multimodal analgesia did not reduce opioid consumption or enhance postoperative pain control and functional recovery in THA patients.
Study context
- Population
- Adults undergoing primary unilateral total hip arthroplasty with multimodal analgesia including non-steroidal anti-inflammatory drugs (NSAIDs)
- Participants
- 60 adults
- Comparison
- Quadratus lumborum block (QLB) vs Placebo
- QLBn = 30
- Placebon = 30reference
- Primary endpoint
- Cumulative opioid consumption in oral morphine equivalents (OMEs)
- Follow-up
- First 24 postoperative hours
Methodological detailsplacebo-controlled, two-center
- Placebo-controlled
- Two-center
Primary result
As reported in the abstract
Cumulative opioid consumption (OMEs) · 24 h postoperatively
- QLB vs Placebo: P = 0.6
Secondary outcomes
Patient experience, pain scores and opioid consumption
- Similar between groups
Rehabilitation outcomes · 3 months
- Did not differ between groups
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Anterior quadratus lumborum block in total hip arthroplasty: a two-center, randomized, placebo-controlled trial showing no additional benefit over multimodal analgesia. Reg Anesth Pain Med. Published 10 February 2025. doi:10.
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