Anticoagulation initiation during extracorporeal membrane oxygenation (ECMO) in trauma patients with traumatic intracranial hemorrhage: A narrative review and conceptual time-dependent risk framework
Authors' conclusion
Despite originating from separate populations, multiple independent lines of evidence converge directionally on declining hemorrhagic risk and rising thrombotic risk over time.
Study context
- Population
- Trauma patients with traumatic intracranial hemorrhage (tICH) requiring ECMO
- Outcome
- Time course of hemorrhagic progression after tICH and thrombotic complications during anticoagulation-free ECMO
Methodological detailsconceptual time-dependent risk framework, Focused search of PubMed, Embase, and the Cochrane Library
- Conceptual time-dependent risk framework
- Focused search of PubMed, Embase, and the Cochrane Library
Main finding
As reported in the abstract
Thrombotic complication rate with anticoagulation-free ECMO over a median support duration of 4.75 days
≈23%
Original publication
Anticoagulation initiation during ECMO in trauma patients with traumatic intracranial hemorrhage: A narrative review and conceptual time-dependent risk framework. J Crit Care. Published 14 July 2026. doi:10.
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