Cardiac arrest & resuscitation
Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest
Main finding · Unfavorable outcome at 1 yearResult — go to the resultOdds ratio 1.12 95% CI 1.04–1.20Authors' conclusion
In this cohort study of children with cardiac arrest, brain features seen on MRI and MRS performed within 2 weeks after arrest were associated with 1-year outcomes
Study context
- Population
- Children aged 48 hours to 17 years resuscitated from in-hospital or out-of-hospital cardiac arrest, PICUs at 14 US hospitals, 2017–2020
- Participants
- 98 children · 14 US hospitals
- Exposure
- Magnetic resonance imaging (MRI) vs magnetic resonance spectroscopy (MRS)
- MRIn = 66
- MRSn = 32
- Outcome
- Unfavorable outcome:
- Death or survival with Vineland Adaptive Behavior Scales
- Third Edition
- Score <70
- Follow-up
- 1 year after cardiac arrest
Methodological detailsblinded neuroradiologist scoring
- Blinded neuroradiologist scoring
Main finding
Unfavorable outcome at 1 year · 1 year
Odds ratio
1.12
95% CI 1.04–1.20
Events by group
Brain MRI and MRS features in children with unfavorable vs favorable 1-year outcome
OR 1.12 (95% CI 1.04–1.20)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Median
| Outcome | Unfavorable outcome | Favorable outcome |
|---|---|---|
| MRI Injury Score (max 34) by outcome | 22 (IQR 7–32) | 1 (IQR 0–8) |
Original publication
Assessment of Brain Magnetic Resonance and Spectroscopy Imaging Findings and Outcomes After Pediatric Cardiac Arrest. JAMA Netw Open. Published 1 June 2023. doi:10.
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