Perioperative medicine & outcomes

Assessment of risk factors for the development of postoperative hypotension in patients undergoing colorectal surgery: a historical cohort study

Can J AnaesthPublished Historical cohort study

Authors' conclusion

Epidural analgesia was associated with postoperative hypotension.

Study context

Population
Adults undergoing colorectal surgery for any indication, Jewish General Hospital, Montreal, Canada, January 2013–December 2017
Participants
982 adults
Exposure
Preoperative modifiable and nonmodifiable risk factors for postoperative hypotension
Outcome
Postoperative hypotension (SBP < 90 mm Hg or need for vasopressor infusion in PACU or on POD 0-3 on the surgical ward)
Follow-up
Postoperative days 0-3
Methodological detailssingle-centre, university-affiliated tertiary care centre, multivariable logistic regression, bootstrap model validation
  • Single-centre
  • University-affiliated tertiary care centre
  • Multivariable logistic regression
  • Bootstrap model validation

Main finding

As reported in the abstract

Incidence of postoperative hypotension and associated risk factors
Adjusted odds ratio (95% CI)P value
Epidural analgesiamodifiable risk factor
2.32(1.52–3.57)
P < 0.001
Preoperative beta-blocker usemodifiable risk factor
1.71(1.04–2.83)
P = 0.04
Laparoscopic surgeryprotective factor
0.48(0.30–0.78)
P = 0.003
Higher preoperative SBPprotective factor
0.97(0.96–0.98)
P < 0.001
Postoperative hypotension occurred
272 (28%)

Observational data: associations, not effects.

Original publication

Assessment of risk factors for the development of postoperative hypotension in patients undergoing colorectal surgery: a historical cohort study. Can J Anaesth. Published 15 June 2026. doi:10.1007/s12630-026-03138-y

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