Perioperative medicine & outcomes
Association of anesthesia and analgesia with long-term mortality after hip fracture surgery: an analysis of the Australian and New Zealand hip fracture registry
Main finding · All-cause 12-month mortalityResult — go to the resultHazard ratio 1.17 95% CI 1.04–1.31Authors' conclusion
There was no difference in the association of 12-month mortality between general and spinal anesthesia in patients undergoing hip fracture surgery. However, there was an association with a higher risk of 12-month mortality in patients who received both general and spinal anesthesia for the same surgery. Patients who received a regional nerve block in both the ED and the OT had a lower association of 12-month and longer-term mortality risk.
Study context
- Population
- Patients undergoing hip fracture surgery, Australian and New Zealand Hip Fracture Registry, 2016–2018
- Participants
- 17,635 patients
- Exposure
- Anesthesia type and regional nerve blocks
- Outcome
- All-cause mortality
- Follow-up
- 12 months
Methodological detailsbinational registry (Australian and New Zealand Hip Fracture Registry), minimum follow-up 12 months
- Binational registry (Australian and New Zealand Hip Fracture Registry)
- Minimum follow-up 12 months
Main finding
All-cause 12-month mortality
Hazard ratio
1.17
95% CI 1.04–1.31
P < 0.001
As reported in the abstract
- Overall 12-month mortality
- 30.6% (n=5410)
Observational data: associations, not effects.
Further findings
Long-term mortality, nerve block in emergency department (ED) and operating theater (OT) · median follow-up 21 months
| HR (95% CI) | P value | ||
|---|---|---|---|
| Nerve block in ED and OTUnimputed unadjusted | 0.86 (0.77–0.96) | P = 0.043 | |
| 0.512Hazard ratio (log scale) |
Original publication
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