Pediatric anesthesia & critical care

Association Between Age- and Sex-Specific Body Mass Index Percentile and Multiple Intubation Attempts: A Retrospective Cohort Analysis

Anesth AnalgPublished Retrospective cohort study

Main finding · Difficult intubation per 10-unit increase in BMI percentileResult — go to the resultOdds ratio 0.98 95% CI 0.95–1.005

Authors' conclusion

Age- and sex-specific BMI percentile was not associated with difficult intubation in children between 2 and 18 years of age.

Study context

Population
Pediatric patients aged 2–18 years having noncardiac surgery with oral endotracheal intubationincluded in the analysis
Participants
9,339 patients
Exposure
Age- and sex-specific body mass index (BMI) percentile
Outcome
Difficult intubation (>1 intubation attempt)
Methodological detailsconfounder-adjusted multivariable logistic regression
  • Confounder-adjusted multivariable logistic regression

Main finding

As reported in the abstract

Difficult intubation per 10-unit increase in BMI percentile

Odds ratio

0.98

95% CI 0.95–1.005

BMI percentile, per 10-unit increase
OR 0.98 (95% CI 0.95–1.005)

Per 10-unit increase, as printed

Difficult intubation, overall
492 (5.3%)
Median [quartiles] age- and sex-specific BMI percentile
70 [33, 93]

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)P value
Difficult intubation in patients with preoperative substantial airway abnormalities (subgroup)Lower odds of difficult intubation0.83 (0.70–0.98)P = 0.01

Difficult intubation by age group (early childhood, middle childhood, early adolescence) (subgroup)

Association consistent across the 3 age groups
  • Interaction P = .53

Original publication

Association Between Age- and Sex-Specific Body Mass Index Percentile and Multiple Intubation Attempts: A Retrospective Cohort Analysis. Anesth Analg. Published 15 March 2023. doi:10.1213/ane.0000000000006400

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