Pediatric anesthesia & critical care
Association between arterial spin labelling (ASL) MRI-derived cerebral blood flow and outcomes after pediatric cardiac arrest
Main finding · Whole brain CBF (pulsed ASL MRI)Result — go to the resultAdjusted odds ratio 19.08 95% CI 1.94–187.41Authors' conclusion
CBF measured 3-5 days after pediatric cardiac arrest by ASL MRI was independently associated with unfavorable outcome.
Study context
- Population
- Patients ≤18 years with clinically obtained brain MRI within 7 days of cardiac arrest, June 2005–December 201969% unfavorable outcome
- Participants
- 48 patients
- Exposure
- Unfavorable vs favorable neurologic outcome
- Outcome
- Unfavorable neurologic status (change in PCPC ≥1 from pre-arrest resulting in hospital discharge PCPC 3-6)
- Follow-up
- Hospital discharge
Main finding
Whole brain CBF (pulsed ASL MRI)
Adjusted odds ratio
19.08
95% CI 1.94–187.41
By group
Greater whole brain CBF
aOR 19.08 (95% CI 1.94–187.41)
As reported in the abstract
Observational data: associations, not effects.
Further findings
- Time from arrest to MRI 4 [3,5] days, similar between outcome groups
- P = 0.39
Original publication
Association between ASL MRI-derived cerebral blood flow and outcomes after pediatric cardiac arrest. Resuscitation. Published 26 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →