Cardiac arrest & resuscitation
Association between body mass index and survival outcomes for in-hospital cardiac arrest
Authors' conclusion
For patients with IHCA, underweight patients had lower rates of survival and favorable neurological survival, regardless of initial cardiac arrest rhythm. In contrast, overweight and obese patients had better outcomes only when the initial rhythm was shockable.
Study context
- Population
- In-hospital cardiac arrest (IHCA) patients with body mass index (BMI) data, Get With The Guidelines-Resuscitation, 2006–2012
- Participants
- 56,411 patients
- Exposure
- BMI categories vs normal BMI
- Outcome
- Favorable neurological survival (discharge cerebral performance category score of 1) and survival to discharge
Methodological detailsmulticentre registry, multivariable hierarchical models with hospital as random effect
- Multicentre registry
- Multivariable hierarchical models with hospital as random effect
Main finding
As reported in the abstract
Favorable neurological survival (discharge cerebral performance category 1), shockable rhythm (subgroup)
Each group vs normalAOR for favorable neurological survival (95% CI)
Underweight
0.64(0.49–0.84)
Overweight
1.17(1.04–1.33)
Obese
1.16(1.00–1.34)
Very obese
1.06(0.91–1.24)
- Favorable neurological survival, shockable rhythm (all BMI groups)
- 3014 (29.4%)
Observational data: associations, not effects.
Further findings
| Outcome | OR (CI) | |
|---|---|---|
| Non-shockable rhythm (subgroup)Underweight vs Normal · favorable neurological survival, adjusted | 0.76 (0.66–0.89) | |
| Non-shockable rhythm (subgroup)Underweight vs Normal · survival to discharge, adjusted | 0.85 (0.75–0.95) | |
| 0.512Odds ratio (log scale) |
- Non-shockable rhythm (subgroup) — Favorable neurological survival among 46,192 patients with non-shockable rhythm
- 4844 (10.4%)
- Non-shockable rhythm (subgroup) — Survival to discharge among patients with non-shockable rhythm
- 7,331 (15.8%)
Non-shockable rhythm (subgroup)
- Other BMI groups: similar rates of both outcomes
Original publication
Association between body mass index and survival outcomes for in-hospital cardiac arrest. Resuscitation. Published 9 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →