Pediatric anesthesia & critical care

Intubation Trends and Survival in Pediatric In-Hospital Cardiac Arrest

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

In this cohort study of pediatric patients with IHCA between 2017 and 2022 without an advanced airway at the start of CPR, no association was identified between intra-arrest tracheal intubation and hospital survival after time-dependent propensity score matching.

Study context

Population
Pediatric patients (<18 years) with in-hospital cardiac arrest (IHCA) and no advanced airway at CPR onset, AHA Get With The Guidelines-Resuscitation registry, 2000–2022 (matched analysis 2017–2022)
Participants
3,262 patients
Exposure
Intubation vs Nonintubation
Outcome
Survival to hospital discharge
Methodological detailstime-dependent propensity matched, multicenter registry
  • Time-dependent propensity matched
  • Multicenter registry

Main finding

As reported in the abstract

Survival to hospital discharge (2017-2022 cohort)
Intubation vs NonintubationEstimate (95% CI)P value
After time-dependent propensity matching
aOR for discharge survival 1.18(0.90–1.53)
P = 0.23
Unadjusted
OR for discharge survival 0.18(0.14–0.24)
P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeaOR for discharge survival (95% CI)P value
Survival to hospital discharge, children aged 8 years or older (subgroup)After matching1.91 (1.09–3.33)P = 0.02

Intubation rate over time

Intubation rate in 2000
33 of 39 [84.6%]
Intubation rate in 2022
112 of 168 [66.7%]
Trend
P < 0.001

Original publication

Intubation Trends and Survival in Pediatric In-Hospital Cardiac Arrest. JAMA Netw Open. Published 3 November 2025. doi:10.1001/jamanetworkopen.2025.44365

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