Pediatric anesthesia & critical care
Outcomes of Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest Among Children With Noncardiac Illness Categories*
Main finding · Survival to hospital dischargeResult — go to the resultAOR for survival to discharge 1.42 95% CI 0.84–2.40Authors' conclusion
ECPR usage increased substantially for the last 20 years. We failed to identify a significant association between ECPR and survival to hospital discharge, although a post hoc Bayesian analysis suggested a survival benefit (85% posterior probability).
Study context
- Population
- Children (<18 yr) with noncardiac illness category receiving ≥30 minutes of cardiopulmonary resuscitation (CPR) for IHCA, AHA Get With The Guidelines-Resuscitation registry, 2000–2021
- Participants
- 875 children
- Exposure
- Extracorporeal cardiopulmonary resuscitation (ECPR) vs conventional CPR
- ECPRn = 159
- Conventional CPR (CCPR)n = 716reference
- Outcome
- Survival to hospital discharge
Methodological detailsmulticentre registry, propensity score weighting, Bayesian logistic regression
- Multicentre registry
- Propensity score weighting
- Bayesian logistic regression
Main finding
As reported in the abstract
AOR for survival to discharge
1.42
95% CI 0.84–2.40
P = 0.19
By group
ECPR vs CCPR
aOR for survival to discharge 1.42 (95% CI 0.84–2.40); P = 0.19
- Bayesian posterior probability of a positive effect of ECPR on survival to discharge (post hoc)
- 85.1%
Observational data: associations, not effects.
Secondary outcomes
Temporal trend in ECPR use
- ECPR use increased over time
- P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes of Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest Among Children With Noncardiac Illness Categories*. Crit Care Med. Published 29 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →