Association between comorbidities at ICU admission and post-Sepsis physical impairment: A retrospective cohort study
Main findingResult — go to the resultRelative risk 1.02 95% CI 0.92–1.14Authors' conclusion
Pre-existing comorbidities prior to ICU admission were not associated with an increased risk of physical impairment at hospital discharge among sepsis patients after adjusting for baseline covariates and in-hospital mortality.
Study context
- Population
- Consecutive adults admitted to an ICU with sepsis, tertiary community hospital (Kameda Medical Center), September 2014 to October 2020analysed
- Participants
- 889 adults
- Exposure
- Pre-existing comorbidities vs no comorbidities at ICU admission
- Comorbiditiesn = 668
- No comorbiditiesn = 221reference
- Outcome
- Physical impairment
- Follow-up
- Hospital discharge
Methodological detailssingle-centre, inverse probability attrition weighting using machine learning
- Single-centre
- Inverse probability attrition weighting using machine learning
Main finding
As reported in the abstract
Relative risk
1.02
95% CI 0.92–1.14
Comorbidities vs No comorbidities
RR 1.02 (95% CI 0.92–1.14)
Observational data: associations, not effects.
Original publication
Association between comorbidities at ICU admission and post-Sepsis physical impairment: A retrospective cohort study. J Crit Care. Published 22 May 2024. doi:10.
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