ICU sedation, delirium & recovery
Association between inflammation and post‐intensive care syndrome: a systematic review
Authors' conclusion
Overall, there was mixed evidence of a potential association between an inflammatory process and long-term patient outcomes following critical illness.
Study context
- Population
- Survivors of critical illness32 studies
- Outcome
- Biomarkers sampled in ≥5 studies associated with PICS outcomes
Methodological detailsVariability in biomarkers sampled, sampling time-points and outcome measures
- Variability in biomarkers sampled, sampling time-points and outcome measures
Pooled result
As reported in the abstract
Interleukin-8 showed associations (% of studies)
71%
C-reactive protein showed associations (% of studies)
62%
Interleukin-10 showed associations (% of studies)
60%
Further pooled results
- Nine studies in a brain injury subgroup analysis
- 9
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association between inflammation and post‐intensive care syndrome: a systematic review. Anaesthesia. Published 20 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →