Perioperative medicine & outcomes
Association between intraoperative body temperature and postoperative delirium: A retrospective observational study
Authors' conclusion
Intraoperative hypothermia (even mild hypothermia) was significantly associated with an increased risk of postoperative delirium.
Study context
- Population
- Adults having major noncardiac surgery under GA for at least two hours, tertiary university hospital, 2019–2021analysed
- Participants
- 27,674 adults
- Exposure
- Severe or mild intraoperative hypothermia vs normothermia
- Severe hypothermian = 388
- Mild hypothermian = 11,779
- Normothermian = 15,507reference
- Outcome
- Risk of delirium
- Follow-up
- Within seven days after surgery
Methodological detailssingle-centre, multivariable logistic regression, Cox regression
- Single-centre
- Multivariable logistic regression
- Cox regression
Main finding
As reported in the abstract
Each group vs normothermiaAdjusted odds ratio (95% CI)
Severe hypothermia
1.43(1.04–1.97)
Mild hypothermia
1.15(1.02–1.28)
Observational data: associations, not effects.
Further findings
| Outcome | aHR (95% CI) | |
|---|---|---|
| Cumulative development of delirium (Cox regression)Mild hypothermia vs Normothermia | 1.14 (1.03–1.26) | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Association between intraoperative body temperature and postoperative delirium: A retrospective observational study. J Clin Anesth. Published 14 March 2023. doi:10.
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