Cardiothoracic & vascular anesthesia
Intraoperative high and low blood pressures are not associated with delirium after cardiac surgery: A retrospective cohort study
Authors' conclusion
This large single-center cohort analysis found no evidence that exposure to high or low blood pressures during various intraoperative phases of cardiac surgery are associated with postoperative delirium.
Study context
- Population
- Adults (≥18 y) having cardiac surgery requiring CPB (excluding deep hypothermic circulatory arrest), Cleveland Clinic Main Campus, January 2017–December 2020
- Participants
- 11,382 adults
- Exposure
- Intraoperative hypotension and hypertension before, during and after CPB
- Outcome
- Postoperative delirium
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Confounder-adjusted associations of hypotension and hypertension with postoperative delirium not statistically significant or clinically meaningful before, during, or after CPB
- Multivariable logistic regression, confounder-adjusted
Observational data: associations, not effects.
Further findings
Postoperative delirium incidence
- Postoperative delirium, 678 of 11,382 patients
- 6.0 %
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Intraoperative high and low blood pressures are not associated with delirium after cardiac surgery: A retrospective cohort study. J Clin Anesth. Published 27 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →