Cardiothoracic & vascular anesthesia
Preoperative Hematocrit Is Not Associated With Stroke After Surgery for Acute Type A Aortic Dissection
Main finding · Postoperative strokeResult — go to the resultOdds ratio 1.00 95% CI 0.99–1.00Authors' conclusion
Preoperative hematocrit was not associated with stroke or mortality after ATAAD repair.
Study context
- Population
- Patients undergoing open acute type A aortic dissection repair under deep hypothermic circulatory arrest, 2010–2021, excluding preoperative cerebral malperfusion syndrome
- Participants
- 527 patients
- Exposure
- Low or high vs normal preoperative hematocrit
- Normal hematocritn = 355reference
- Low hematocritn = 143
- High hematocritn = 29
- Outcome
- Postoperative stroke
Methodological detailssingle-centre, consecutive patients, multivariable adjustment
- Single-centre
- Consecutive patients
- Multivariable adjustment
Main finding
As reported in the abstract
Odds ratio
1.00
95% CI 0.99–1.00
P = 0.79
Hematocrit
OR 1.00 (95% CI 0.99–1.00); P = 0.79
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| In-hospital mortalityLow hematocrit vs Normal hematocrit | 1.59 (0.77–3.28) | P = 0.21 | |
| In-hospital mortalityHigh hematocrit vs Normal hematocrit | 2.48 (0.74–8.29) | P = 0.14 | |
| 0.10.31310Odds ratio (log scale) |
- In-hospital mortality — Lower unadjusted in-hospital mortality with normal hematocrit
- p = 0.02
Safety
- Lower transfusion rates with normal hematocrit
- P < 0.001
- Re-exploration for bleeding similar across groups
- P = 0.68
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Preoperative Hematocrit Is Not Associated With Stroke After Surgery for Acute Type A Aortic Dissection. J Cardiothorac Vasc Anesth. Published 6 January 2025. doi:10.
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