Cardiothoracic & vascular anesthesia
Cerebral Oximetry Index–Guided Blood Pressure Management During Cardiopulmonary Bypass Reduces Postoperative Delirium in Patients with Acute Type A Aortic Dissection
Authors' conclusion
COx-guided blood pressure management during CPB was associated with reduced incidence and severity of POD following ATAAD surgery.
Study context
- Population
- Patients undergoing acute type A aortic dissection repair with cardiopulmonary bypass (CPB)
- Participants
- 157 patients
- Comparison
- COx-guided vs conventional BP management during CPB
- COx-guidedn = 76
- Conventionaln = 81reference
- Primary endpoint
- Postoperative delirium (POD) incidence
- Follow-up
- First 7 postoperative days
Methodological detailsprospective
- Prospective
Primary result
As reported in the abstract
P = 0.039
Secondary outcomes
POD duration
P = 0.045
ICU stay
P = 0.042
Time to extubation
P = 0.027
| Outcome | COx-guided | Conventional | P value |
|---|---|---|---|
| Delirium severity (Delirium Rating Scale-Revised-98 score) | 5 | 10 | P = 0.033 |
Safety
Postoperative cerebral infarction
P = 0.037
AKI
P = 0.042
Original publication
Cerebral Oximetry Index–Guided Blood Pressure Management During Cardiopulmonary Bypass Reduces Postoperative Delirium in Patients with Acute Type A Aortic Dissection. J Cardiothorac Vasc Anesth. Published 9 January 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →