Cardiothoracic & vascular anaesthesia
Intraoperative hypotension and its association with acute kidney injury in patients undergoing elective cardiac surgery: a large retrospective cohort study
Main finding · Postoperative AKIResult — go to the resultOdds ratio 1.004 95% CI 1.003–1.005Authors' conclusion
The cumulative duration of IOH is an independent risk factor for the occurrence of postoperative AKI after cardiac surgery.
Study context
- Population
- Patients undergoing elective cardiac surgery, academic university hospital (Bad Oeynhausen, Germany), 2009–2018
- Participants
- 28,909 patients
- Exposure
- Cumulative duration of intraoperative hypotension (IOH) and postoperative acute kidney injury (AKI)
- Outcome
- Incidence of AKI (KDIGO criteria)
Methodological detailssingle-centre
- Single-centre
Main finding
Postoperative AKI
Odds ratio
1.004
95% CI 1.003–1.005
P < 0.001
Cumulative duration of IOH (minutes)
OR 1.004 (95% CI 1.003–1.005); P < 0.001
As reported in the abstract
- Incidence of postoperative AKI
- 42.9%
Observational data: associations, not effects.
Secondary outcomes
Independent predictors of AKI (logistic regression)
- Eight predictors: age, cumulative duration of IOH, duration of surgery, COPD, BMI, type of surgery, ASA stage, Euroscore 2
Survival time
- Significantly shorter with higher cumulative IOH duration, age >70 years, and AKI
- P < 0.001
Original publication
Intraoperative hypotension and its association with acute kidney injury in patients undergoing elective cardiac surgery: a large retrospective cohort study. Eur J Anaesthesiol Intensive Care. Published 15 February 2024. doi:10.
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