Cardiothoracic & vascular anesthesia
Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery
Main finding · AKI per 5-min joint hypotension/CI≤2Result — go to the resultAdjusted odds ratio 1.11 95% CI 1.02–1.22Authors' conclusion
Joint exposure to hypotension/CI≤2 during cardiac surgery was associated with AKI and increased LOS, whereas exposure to hypotension/CI>2 was not.
Study context
- Population
- Adults undergoing coronary artery bypass surgery with CPB379 (30%) exposed to ≥5 min hypotension/low CI
- Participants
- 1,272 adults
- Exposure
- Duration of joint hypotension with low CI vs other joint mean arterial pressure (MAP)/CI ranges
- Outcome
- AKI
Main finding
AKI per 5-min joint hypotension/CI≤2
Adjusted odds ratio
1.11
95% CI 1.02–1.22
P = 0.021
Hypotension/CI≤2 (per 5-min)
adjusted OR 1.11 (95% CI 1.02–1.22); P = 0.021
Per 5-min, as printed
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Adjusted time ratio (95% CI) | P value |
|---|---|---|
| ICU LOS | 1.04 (1.02–1.07) | P = 0.002 |
| Hospital LOS | 1.02 (1.00–1.03) | P = 0.009 |
ICU length of stay (LOS)
- Hypotension/CI>2 not associated with increased LOS
Original publication
Low cardiac index during periods of arterial hypotension and risk of acute kidney injury in cardiac surgery. Br J Anaesth. Published 6 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →