Cardiothoracic & vascular anesthesia
Effect of preoperative risk on the association between intraoperative hypotension and postoperative acute kidney injury in cardiac surgery
Authors' conclusion
IOH is a significant independent risk factor for AKI after cardiac surgery. Patients with higher baseline risk showed a more prominent relationship between IOH and postoperative AKI than low-risk patients.
Study context
- Population
- Patients undergoing cardiac surgery
- Exposure
- Intraoperative hypotension (IOH) vs less IOH, by preoperative risk group
- Outcome
- Postoperative AKI
Methodological detailssingle-centre, stratified by preoperative risk
- Single-centre
- Stratified by preoperative risk
Main finding
As reported in the abstract
Association between IOH and postoperative AKI, by preoperative risk group (subgroup)
Adjusted odds ratio (95% CI)
High-risk: IOH cumulative duration >104 minfirst of two adjusted ORs printed
2.27(1.10–4.74)
High-risk: IOH cumulative duration >104 minsecond of two adjusted ORs printed
3.63(1.77–7.58)
High-risk: IOH AUC >905 mmHg minfirst of two adjusted ORs printed
2.08(1.01–4.36)
High-risk: IOH AUC >905 mmHg minsecond of two adjusted ORs printed
4.00(1.95–8.43)
Observational data: associations, not effects.
Further findings
Preoperative risk factors identified
- Ten risk factors: age, smoking status, NYHA III/Ⅳ, emergency surgery, peripheral vascular disease, cerebrovascular disease, HF, hypertension, previous cardiac surgery, NT-proBNP concentration
- 10
Original publication
Effect of preoperative risk on the association between intraoperative hypotension and postoperative acute kidney injury in cardiac surgery. Anaesth Crit Care Pain Med. Published 13 April 2023. doi:10.
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