The association between intraoperative hypotension and postoperative acute kidney injury following emergent critical cesarean delivery: a retrospective cohort study
Main finding · Postoperative AKI vs cumulative IOH durationResult — go to the resultAdjusted odds ratio 1.036 95% CI 1.013–1.060Authors' conclusion
Our findings demonstrate that IOH was independently associated with a higher incidence of postoperative AKI in patients who underwent an emergent critical cesarean delivery.
Study context
- Population
- Patients who underwent emergent critical cesarean delivery, January 2019 to August 2024
- Participants
- 508 patients
- Exposure
- Association of intraoperative hypotension with postoperative acute kidney injury (AKI)
- Outcome
- Postoperative AKI (KDIGO, serum creatinine) by primary IOH metric (cumulative duration of MAP <65 mmHg)
Methodological detailsmultivariable logistic regression, sensitivity analyses with alternative intraoperative hypotension (IOH) metrics
- Multivariable logistic regression
- Sensitivity analyses with alternative IOH metrics
Main finding
Postoperative AKI vs cumulative IOH duration
Adjusted odds ratio
1.036
95% CI 1.013–1.060
P = 0.002
Cumulative duration of IOH
aOR 1.036 (95% CI 1.013–1.060); P = 0.002
As reported in the abstract
- Incidence of postoperative AKI
- 69 of the 508 patients (13.58%)
Observational data: associations, not effects.
Further findings
AKI by alternative IOH metrics (sensitivity analyses)
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Hypotensive event countMultivariable logistic regression | 2.098 (1.180–3.732) | P = 0.012 | |
| AUCMultivariable logistic regression | 1.004 (1.001–1.007) | P = 0.009 | |
| TWAMultivariable logistic regression | 1.557 (1.058–2.291) | P = 0.025 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Original publication
The association between intraoperative hypotension and postoperative acute kidney injury following emergent critical cesarean delivery: a retrospective cohort study. J Clin Monit Comput. Published 8 January 2026. doi:10.
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