Perioperative medicine & outcomes

Association Between Intraoperative Perfusion Index and Mortality in Patients Undergoing General Anesthesia for Noncardiac Surgery: A Protocol for an Observational Study

Acta Anaesthesiol ScandPublished Protocol for a retrospective cohort study

Study context

Population
Adults undergoing GA for noncardiac surgery in the Capital and Zealand Regions of Denmark, 2017–2024
Planned comparison
Intraoperative perfusion index
Primary endpoint
30-day all-cause mortality
Follow-up
30 days
Methodological detailsregistry-based, multicentre, Secondary outcome: composite of postoperative complications, Ethics committee waived formal ethical approval (F-24078050), Analysis: adjusted multivariable logistic regression with restricted cubic splines, Data from the AI and Automation in Anesthesia perioperative database
  • Registry-based
  • Multicentre
  • Secondary outcome: composite of postoperative complications
  • Ethics committee waived formal ethical approval (F-24078050)
  • Analysis: adjusted multivariable logistic regression with restricted cubic splines
  • Data from the AI and Automation in Anesthesia perioperative database

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Association Between Intraoperative Perfusion Index and Mortality in Patients Undergoing General Anesthesia for Noncardiac Surgery: A Protocol for an Observational Study. Acta Anaesthesiol Scand. Published 8 December 2025. doi:10.1111/aas.70171

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