Perioperative medicine & outcomes

Association Between Mobilization and Composite Postoperative Complications Following Major Elective Surgery

JAMA SurgPublished Retrospective observational cohort study

Main finding · Composite postoperative complicationsResult — go to the resultHazard ratio 0.75 95% CI 0.67–0.84

Authors' conclusion

In this study, mobilization measured by wearable accelerometers was associated with fewer postoperative complications and shorter hospital length of stay.

Study context

Population
Adults after elective surgery lasting ≥2 hours with ≥48 hours of hospitalization, single quaternary US referral center, February 2017–October 2020of 16,203 potential participants
Participants
8,653 adults
Exposure
Amount of postoperative mobilization per hour over 48 postoperative hours (per 4-minute increase)
  • Primary outcomen = 633
Outcome
Composite of:
  • Myocardial injury
  • Ileus
  • Stroke
  • VTE
  • Pulmonary complications
  • All-cause in-hospital mortality
Methodological detailssingle-centre, wearable accelerometer monitoring
  • Single-centre
  • Wearable accelerometer monitoring

Main finding

Composite postoperative complications

Hazard ratio

0.75

95% CI 0.67–0.84

P < 0.001

Each 4-minute increase in mobilization
HR 0.75 (95% CI 0.67–0.84); P < 0.001

Each 4-minute increase in mobilization, as printed

As reported in the abstract

Patients experiencing the primary outcome
633 (7.3%)

Observational data: associations, not effects.

Secondary outcomes

Mobilization time (minutes per monitored hour) · first 48 postoperative hours

OutcomeEstimated median reduction (days) (95% CI)P value
Hospital LOS0.12 (0.09–0.15)P < 0.001
Mobilization time (minutes per monitored hour) — Overall median mobilization time
3.9 (1.7-7.8)

Pain score and 30-day readmission

No associations between mobilization and pain score or 30-day readmission

Original publication

Association Between Mobilization and Composite Postoperative Complications Following Major Elective Surgery. JAMA Surg. Published 1 August 2023. doi:10.1001/jamasurg.2023.1122

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