Perioperative medicine & outcomes
Preoperative predictors of acute postoperative anxiety and depression using ecological momentary assessments: a secondary analysis of a single-centre prospective observational study
Authors' conclusion
Postoperative worsening anxiety and depression appear to be associated more closely with preoperative active mental health or pain symptoms rather than self-reported history of these conditions.
Study context
- Population
- Patients undergoing surgery lasting >1 h with overnight admission at a university-affiliated quaternary referral centre
- Participants
- 1,168 patients
- Primary endpoint
- Co-primary: worsening anxiety and worsening depression symptoms (slope >0 of thrice-daily EMA modelled as linear function of time)
- Follow-up
- 30 days
Methodological detailsecological momentary assessments, multivariable logistic regression
- Ecological momentary assessments
- Multivariable logistic regression
Primary result
As reported in the abstract
Incidence of postoperative worsening anxiety and depression
Postoperative worsening anxiety
60 patients
5%
Postoperative worsening depression
86 patients
7%
Further findings
Preoperative predictors of postoperative worsening anxiety
| aOR (95% CrI) | ||
|---|---|---|
| Mild preoperative PROMIS anxiety symptomsCredible interval · CrI | 2.48 (1.29–4.79) | |
| Moderate to severe preoperative PROMIS anxiety symptomsCredible interval · CrI | 2.22 (1.10–4.51) | |
| Preoperative painCredible interval · CrI | 3.46 (1.32–9.12) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Preoperative predictors of postoperative worsening depression
| aOR (95% CrI) | ||
|---|---|---|
| Mild preoperative PROMIS depression symptomsCredible interval · CrI | 2.26 (1.24–4.14) | |
| Moderate to severe preoperative PROMIS depression symptomsCredible interval · CrI | 3.79 (2.10–6.81) | |
| 0.10.31310Adjusted odds ratio (log scale) |
Self-reported history of anxiety or depression
- Did not independently predict either outcome
Original publication
Preoperative predictors of acute postoperative anxiety and depression using ecological momentary assessments: a secondary analysis of a single-centre prospective observational study. Br J Anaesth. Published 24 October 2024. doi:10.
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