Neuroanesthesia & neurocritical care
Association between perioperative change in red cell distribution width and mortality in patients with brain tumor craniotomy
Authors' conclusion
Among patients undergoing craniotomy for a brain tumor, a rise in RDW was associated with 30-day mortality and higher long-term mortality risks, even if patients' admissions for RDW values were within the normal range.
Study context
- Population
- Patients undergoing craniotomy for brain tumors, West China Hospital, Sichuan University, January 2011 to March 2021
- Participants
- 9,589 patients
- Exposure
- Perioperative rise or drop in RDW vs non-significant RDW change
- Outcome
- All-cause mortality
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
30-day mortality · 30 days
Each group vs AAdjusted odds ratio (95% CI)
C
3.56(2.56–4.95)
B
1.04(0.53–2.04)
Observational data: associations, not effects.
Further findings
| Outcome | aOR (95% CI) | |
|---|---|---|
| One-year mortalityC vs A | 1.57 (1.33–1.85) | |
| One-year mortalityB vs A | 1.18 (0.92–1.53) | |
| 0.512Adjusted odds ratio (log scale) |
Survival during follow-up (restricted cubic spline)
- Increases in RDW significantly associated with lower survival rates vs stable RDW
Original publication
Association between perioperative change in red cell distribution width and mortality in patients with brain tumor craniotomy. J Clin Anesth. Published 18 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →