Perioperative medicine & outcomes
Association between postoperative delirium and adverse outcomes in older surgical patients: A systematic review and meta-analysis
Authors' conclusion
Postoperative delirium was associated with higher odds of mortality, postoperative complications, unplanned intensive care unit admissions, length of hospital stay, and non-home discharge.
Study context
- Population
- Non-cardiac and non-neurological surgical patients aged ≥60 years; studies with N < 100 excluded
- Participants
- 20,988 participants · 54 studies
- Comparison
- Postoperative delirium vs no postoperative delirium
- Outcome
- Pooled incidence of postoperative delirium
Methodological detailsDatabases searched from inception to February 22, 2022
- Databases searched from inception to February 22, 2022
Pooled result
As reported in the abstract
Elective surgery
19%
95% CI 16%, 23%
Emergency surgery
32%
95% CI 25%, 39%
Further pooled results
| Outcome | OR (95% CI) | |
|---|---|---|
| Mortality, elective surgeryDelirium vs No delirium · 1-month | 6.60 (1.58–27.66) | |
| Mortality, elective surgeryDelirium vs No delirium · 6-month | 5.69 (2.33–13.88) | |
| Mortality, elective surgeryDelirium vs No delirium · 1-year | 2.87 (1.63–5.06) | |
| Mortality, emergency surgeryDelirium vs No delirium · 1-month | 3.56 (1.77–7.15) | |
| Mortality, emergency surgeryDelirium vs No delirium · 6-month | 2.60 (1.88–3.61) | |
| Mortality, emergency surgeryDelirium vs No delirium · 1-year | 2.30 (1.77–3.00) | |
| 0.050.21520Odds ratio (log scale) |
Complications, unplanned ICU admissions, prolonged LOS, non-home discharge, elective surgery
- Higher odds in delirium cases
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association between postoperative delirium and adverse outcomes in older surgical patients: A systematic review and meta-analysis. J Clin Anesth. Published 27 July 2023. doi:10.
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