Neuroanesthesia & neurocritical care
Association between postoperative thrombocytopenia and outcomes after traumatic brain injury surgery: A cohort study
Main findingResult — go to the resultAdjusted odds ratio 0.49 95% CI 0.33–0.75Authors' conclusion
Patients with TBI who experienced postoperative thrombocytopenia were more likely to have a poor short-term prognosis.
Study context
- Population
- Patients who underwent traumatic brain injury (TBI) surgery
- Participants
- 1,093 patients
- Exposure
- Non-thrombocytopenia vs postoperative thrombocytopenia
- Outcome
- Hospital mortality
Methodological detailsMIMIC-III database
- MIMIC-III database
Main finding
As reported in the abstract
Adjusted odds ratio
0.49
95% CI 0.33–0.75
P = 0.01
Non-thrombocytopenia vs Thrombocytopenia
aOR 0.49 (95% CI 0.33–0.75); P = 0.01
Observational data: associations, not effects.
Further findings
Platelet count trajectory, survivors vs non-survivors (generalized additive mixed model (GAMM)) · within 7 days after surgery
- Platelet counts increased over time in both survivors and non-survivors, more noticeably in survivors; difference increased per day on average
- 7.97
Original publication
Association between postoperative thrombocytopenia and outcomes after traumatic brain injury surgery: A cohort study. Acta Anaesthesiol Scand. Published 7 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →