Pediatric anesthesia & critical care

Association between preoperative anaemia, transfusion, and outcomes in children undergoing noncardiac surgery

Br J AnaesthPublished Retrospective cohort study

Authors' conclusion

The incidence of preoperative anaemia and transfusion in children have remained stable in the last 11 yr. Anaemia, transfusion, and the combination of both increased 30-day mortality and the incidence of postoperative complications.

Study context

Population
Children 1–18 yr undergoing noncardiac surgery with a preoperative haematocrit recorded, 2012–2023, ACS NSQIP paediatric databases
Exposure
Preoperative anaemia and perioperative transfusion (4 groups) vs no anaemia, no transfusion
Outcome
30-day mortality and postoperative complications
Follow-up
30 days
Methodological detailsregistry database (ACS NSQIP paediatric)
  • Registry database (ACS NSQIP paediatric)

Main finding

As reported in the abstract

30-day mortality

Observational data: associations, not effects.

Further findings

Incidence of preoperative anaemia

Preoperative anaemia
25.7% (n=110 341)
Remained stable 2012–2023

Overall transfusion rate

Overall transfusion
10.4% (n=44 808)
Remained stable 2012–2023

Original publication

Association between preoperative anaemia, transfusion, and outcomes in children undergoing noncardiac surgery. Br J Anaesth. Published 10 June 2025. doi:10.1016/j.bja.2025.04.050

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