Association Between Whole Blood Transfusion and Mortality Among Injured Pediatric Patients
Main finding · MortalityResult — go to the resultHazard ratio 0.58 95% CI 0.34–0.98Authors' conclusion
The use of WB was associated with improved survival among injured pediatric patients requiring immediate transfusion.
Study context
- Population
- Injured children aged ≤16 years with immediate blood transfusion within 4 hours of hospital arrival, American College of Surgeons Trauma Quality Improvement Program (ACS-TQIP) 2020–2021
- Participants
- 2,729 children · 318 matched pairs
- Exposure
- Whole blood transfusion vs no whole blood (WB)
- WBn = 319
- Outcome
- Survival (mortality)
- Follow-up
- 24 hours and 30 days
Methodological details1:1 propensity score-matched, registry (ACS-TQIP)
- 1:1 propensity score-matched
- Registry (ACS-TQIP)
Main finding
Mortality · 24 hours
Hazard ratio
0.58
95% CI 0.34–0.98
P = 0.042
WB vs No WB
HR 0.58 (95% CI 0.34–0.98); P = 0.042
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Mortality · 30 daysPropensity score-matched cohort | 0.65 (0.46–0.90) | P = 0.011 | |
| 0.512Hazard ratio (log scale) |
Original publication
Association Between Whole Blood Transfusion and Mortality Among Injured Pediatric Patients. Ann Surg. Published 6 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →