Respiratory failure & ventilation
Association Between Spontaneous Breathing Trial Methods and Reintubation in Adult Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials
Pooled result · ReintubationResult — go to the resultRelative risk 0.23 95% CI 0.09–0.51Authors' conclusion
In this study, HFO SBT was associated with a lower risk of reintubation compared with other SBT methods.
Study context
- Population
- Critically ill adults undergoing spontaneous breathing trial (SBT)
- Participants
- 6,196 adults · 22 RCTs
- Comparison
- SBT methods vs T-tube
- T-tuben = 2,135reference
- Pressure support ventilation without positive end-expiratory pressuren = 2,101
- Outcome
- Reintubation
Methodological detailsfrequentist pairwise meta-analysis, SUCRA ranking, GRADE certainty assessment
- Frequentist pairwise meta-analysis
- SUCRA ranking
- GRADE certainty assessment
Pooled result
As reported in the abstract
Relative risk
0.23
95% CI 0.09–0.51
HFO vs T-tube
RR 0.23 (95% CI 0.09–0.51)
Further pooled results
| Outcome | HFO | CPAP |
|---|---|---|
| Probability of being best intervention for reducing reintubation (SUCRA ranking) | 81.86% | 11.8% |
| SUCRA | 96.42 | 76.75 |
Original publication
Association Between Spontaneous Breathing Trial Methods and Reintubation in Adult Critically Ill Patients: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Chest. Published 2 July 2024. doi:10.
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