Association Between State Limits on Opioid Prescribing and the Incidence of Persistent Postoperative Opioid Use Among Surgical Patients
Authors' conclusion
Laws limiting opioid prescriptions were not associated with subsequent reductions in persistent postoperative opioid use.
Study context
- Population
- Privately insured patients undergoing one of 10 procedures, US, January 1, 2004 to September 30, 2018privately insured
- Participants
- 957,639 participants
- Exposure
- State opioid prescribing limit of ≤7 days or >7 days supply vs no limits on the day of surgery
- Outcome
- Persistent postoperative opioid use (filled ≥10 prescriptions or ≥120 days supply of opioids during POD 91-365)
- Follow-up
- Postoperative days 91-365
Methodological detailsdifference-in-differences, adjusted regression
- Difference-in-differences
- Adjusted regression
Main finding
As reported in the abstract
Adjusted incidence of persistent postoperative opioid use
≤7 days supply vs No limits: P = 0.13 · >7 days supply vs No limits: P = 0.43
Observational data: associations, not effects.
Original publication
Association Between State Limits on Opioid Prescribing and the Incidence of Persistent Postoperative Opioid Use Among Surgical Patients. Ann Surg. Published 9 November 2021. doi:10.
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