Pain medicine

Epidemiology of Opioid Prescribing After Discharge From Surgical Procedures Among Adults

JAMA Netw OpenPublished Cross-sectional study

Authors' conclusion

In this cross-sectional study of the distribution of postoperative opioid prescribing in the United States, a small number of common procedures accounted for a large proportion of MMEs dispensed after surgery.

Study context

Population
Adults aged 18 to 64 years, privately insured or Medicaid, undergoing surgical procedures with discharge between December 1, 2020, and November 30, 2021 (Merative MarketScan, US)
Participants
1,040,934 surgical procedures
Exposure
18 to 44 years vs 45 to 64 years
  • 18 to 44 yearsn = 457,016
  • 45 to 64 yearsn = 583,918
Outcome
Proportion of total MMEs dispensed within 3 days of discharge attributable to each procedure type, by age group
Follow-up
Within 3 days of discharge
Methodological detailsclaims database analysis
  • Claims database analysis

Main finding

As reported in the abstract

Proportion of total MMEs dispensed after surgery, top procedures
GroupValueCesarean delivery, morphine milligram equivalents (MMEs)Arthroplasty of knee, MMEsArthroscopy of knee, % of total MMEsArthroscopy of knee, MMEs
18 to 44 years19.4%11 418 658 of 58 825 364
45 to 64 years9.7%5 885 305 of 60 591 5646.5%3 912 616

Value

18 to 44 years19.4%
45 to 64 years9.7%

Cesarean delivery, morphine milligram equivalents (MMEs)

18 to 44 years11 418 658 of 58 825 364
45 to 64 years— not stated in the abstract

Arthroplasty of knee, MMEs

18 to 44 years— not stated in the abstract
45 to 64 years5 885 305 of 60 591 564

Arthroscopy of knee, % of total MMEs

18 to 44 years— not stated in the abstract
45 to 64 years6.5%

Arthroscopy of knee, MMEs

18 to 44 years— not stated in the abstract
45 to 64 years3 912 616
18 to 44 years: cesarean delivery accounted for the highest proportion of total MMEs
19.4%

Observational data: associations, not effects.

Further findings

Procedures with opioid prescriptions dispensed
503 058 (48.3%)

Original publication

Epidemiology of Opioid Prescribing After Discharge From Surgical Procedures Among Adults. JAMA Netw Open. Published 3 June 2024. doi:10.1001/jamanetworkopen.2024.17651

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