Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study
Authors' conclusion
High TyG index is an independent risk factor for AKI in critical ill patients with AP.
Study context
- Population
- Critically ill patients with acute pancreatitis hospitalised in the ICU
- Participants
- 848 patients
- Exposure
- Triglyceride-glucose (TyG) index ≥ 8.78 vs lower TyG index
- Outcome
- Incidence of AKI
Methodological detailsMIMIC-IV database
- MIMIC-IV database
Main finding
As reported in the abstract
Hazard ratio (95% CI)P value
TyG index (continuous)
1.65(1.10–2.48)
P = 0.015TyG index (categorical)
1.72(1.09–2.79)
P = 0.028- Overall incidence of acute kidney injury (AKI)
- 61.56%
- Higher incidence of AKI in TyG index ≥ 8.78 group (Kaplan-Meier)
- P < 0.001
Observational data: associations, not effects.
Secondary outcomes
In-hospital mortality
- Overall in-hospital mortality
- 11.69%
RRT use
- Higher risk of requiring RRT in TyG index ≥ 8.78 group (Kaplan-Meier)
- P < 0.001
Original publication
Association between the triglyceride–glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study. J Intensive Care. Published 5 February 2025. doi:10.
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