Extracorporeal Membrane Oxygenation (ECMO) Weaning Blood Processing: A Scoping Review
Authors' conclusion
Based on current observational evidence, autologous blood reinfusion during ECMO weaning appears feasible and is associated with favorable surrogate hematological outcomes compared with direct discard. Identified strategies differ in indications, operation, and costs, and may be selected individually according to ECMO mode, hemodynamic status, and institutional conditions. Given the limited number, low quality, and high heterogeneity of included studies, no conclusions regarding hard clinical outcomes can be drawn. This review highlights the urgency of high-quality studies with long-term clinical endpoints to further verify efficacy and safety.
Study context
- Population
- Studies of blood processing strategies during ECMO weaningstudies included (of 68 articles retrieved)
- Participants
- 9 participants
- Comparison
- Blood processing strategies during ECMO weaning
- Outcome
- Identified blood processing strategies
Methodological detailsPRISMA-ScR 2018 checklist, JBI methodology, descriptive synthesis and qualitative analysis
- PRISMA-ScR 2018 checklist
- JBI methodology
- Descriptive synthesis and qualitative analysis
Main finding
As reported in the abstract
- Strategies classified into four categories: blood cell salvage system (BCS) autologous reinfusion, pump-controlled blood reinfusion, modified CPD blood bag storage reinfusion, and direct discard
Further findings
Literature search
- Articles retrieved
- 68
- Studies finally included
- 9
Original publication
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