ICU sedation, delirium & recovery
Association between type II diabetes mellitus and 90-day mortality in a large multicenter prospectively collected cohort. A FROG ICU post-hoc study
Primary result · 90-day mortality, PS-matchedResult — go to the resultHazard ratio 0.81 CI 0.56–1.18Authors' conclusion
In the present study, T2DM was not associated with 90-day mortality post ICU admission.
Study context
- Population
- ICU patients ventilated and/or treated by a vasoactive agent for >24 h16% with T2DM
- Participants
- 2,002 patients
- Comparison
- T2DM vs no T2DM
- Primary endpoint
- Mortality
- Follow-up
- 90 days post ICU admission
Methodological detailsmulticentre, prospectively collected, propensity-score matched, imputed datasets
- Multicentre
- Prospectively collected
- Propensity-score matched
- Imputed datasets
Primary result
90-day mortality, PS-matched · 90 days
Hazard ratio
0.81
CI 0.56–1.18
T2DM vs no T2DM
HR 0.81 (CI 0.56–1.18)
As reported in the abstract
Further findings
| Outcome | HR (CI) | |
|---|---|---|
| 90-day mortality, unmatched cohort · unmatched cohort | 1.35 (1.1–1.65) | |
| 0.512Hazard ratio (log scale) |
90-day mortality, imputed datasets
- Results similar on imputed datasets; pooled HR
- 0.95 (0.69-1.30) (CI)
Baseline severity at inclusion (T2DM vs no T2DM)
- SAPSII score, T2DM vs no T2DM (more severely ill)
- 51(39-67) vs 48(35-61), p < 0.0001
- Charlson score, T2DM vs no T2DM
- 2(1-3) vs 0(0-2), p < 0.0001
Original publication
Association between type II diabetes mellitus and 90-day mortality in a large multicenter prospectively collected cohort. A FROG ICU post-hoc study. J Crit Care. Published 27 October 2022. doi:10.
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