The association between venous excess ultrasound grading system (VExUS) and major adverse kidney events after 30 days in critically ill patients: A prospective cohort study
Main findingResult — go to the resultOdds ratio 4.3 95 % CI 1.2–20.7Authors' conclusion
In critically ill patients the prevalence of VExUS 2 and 3 is low. VExUS is strongly associated with relevant patient outcomes and is a reliable tool in assessing venous congestion.
Study context
- Population
- Consecutive adult critically ill patients expected to stay in intensive care unit (ICU) ≥ 24 h with feasible ultrasound, tertiary hospital ICU in the Netherlands
- Participants
- 138 patients
- Exposure
- VExUS grade ≥ 2 vs lower grades
- Outcome
- Prevalence of VExUS grades and association with major adverse kidney events (MAKE-30: rise of ≥200 % in serum creatinine, use of RRT or death)
- Follow-up
- First 30 days after admission
Methodological detailssingle centre
- Single centre
Main finding
As reported in the abstract
Odds ratio
4.3
95 % CI 1.2–20.7
By group
VExUS grade ≥ 2 vs lower grades
OR 4.3 (95 % CI 1.2–20.7)
Observational data: associations, not effects.
Further findings
Change of VExUS during admission
- VExUS grades showed the most change within the first 72 h after ICU admission
Inter- and intra-rater agreement
- Moderate to excellent inter- and intra-rater agreement
Original publication
The association between venous excess ultrasound grading system (VExUS) and major adverse kidney events after 30 days in critically ill patients: A prospective cohort study. J Crit Care. Published 25 April 2025. doi:10.
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