Association of intra-operative red blood cell transfusion on the systemic immune index and recovery in patients undergoing cesarean section: a large propensity score-matched study
Authors' conclusion
Intraoperative blood transfusion for cesarean section was associated with increased levels of systemic inflammation indicators, higher post-operative complication rates, and prolonged hospital stay.
Study context
- Population
- Patients undergoing cesarean section at a single hospital, January 2016–June 2020322 matched
- Participants
- 1,231 patients
- Exposure
- Intra-operative RBC transfusion vs no transfusion
- Outcome
- LOS
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
P = 0.026
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| LOS (multivariate analysis) | 1.52 (1.07–2.25) | |
| 0.512Hazard ratio (log scale) |
Systemic inflammation indicators · post-operative day (POD) 1 and POD3
- Increased significantly from pre-operative baseline in both groups
Safety
Vomiting
P = 0.032
Fever
P = 0.032
Wound complications
P = 0.028
Intestinal obstruction
P = 0.034
Original publication
Association of intra-operative red blood cell transfusion on the systemic immune index and recovery in patients undergoing cesarean section: a large propensity score-matched study. Perioper Med (Lond). Published 8 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →