Obstetric anesthesia

Role of cosyntropin in the prevention of post-dural puncture headache: a propensity-matched retrospective analysis

Int J Obstet AnesthPublished Retrospective cohort study

An erratum to this article was published (Int J Obstet Anesth, Nov 2024 ↗)

Authors' conclusion

Prophylactic administration of cosyntropin is not associated with a reduced incidence of PDPH.

Study context

Population
Parturients with accidental dural puncture at a large tertiary-care center, June 1, 2018 to Oct 31, 2021115 analysed
Participants
132 participants
Exposure
Cosyntropin vs No-cosyntropin
  • Cosyntropinn = 65
Outcome
Incidence of post-dural puncture headache (PDPH)
Methodological detailspropensity-score matched, single-centre
  • Propensity-score matched
  • Single-centre

Main finding

As reported in the abstract

PDPH

P = 0.08

Observational data: associations, not effects.

Further findings

Epidural blood patch

P = 0.70

Original publication

Role of cosyntropin in the prevention of post-dural puncture headache: a propensity-matched retrospective analysis. Int J Obstet Anesth. Published 11 August 2023. doi:10.1016/j.ijoa.2023.103922

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